Flanker Hamish Watson returns to the Scotland XV in one of six changes for their final Six Nations game of the campaign against England.
Watson, who impressed off the bench in the defeat by Wales, replaces the injured Jamie Ritchie, with Sam Skinner also introduced to the back row. Lock Ben Toolis is in for Jonny Gray.
Sean Maitland and Byron McGuigan replace injured duo Blair Kinghorn and Tommy Seymour in the back three, and Sam Johnston is included at centre with Pete Horne dropping out.
Scotland, who have lost their last three matches after an opening win over Italy, travel to Twickenham in search of a first victory over England there since 1983.
“Were delighted to bring back Hamish into the starting line-up,” said coach Gregor Townsend. “He made a real impact on Saturday and we have no doubt that hes ready to take the game to the opposition in attack and defence.
“We have to build on the positive aspects of our performance against Wales. The players showed in the second-half what the team is capable of against one of the best sides in the world. The next step is making that pressure count on the scoreboard, more regularly.
“Winning away from home tends to be achieved through an outstanding defensive performance and we are determined to deliver that this Saturday.”
Scotland: Maitland; Graham, Grigg, Johnson, McGuigan; Russell, Price; Dell, McInally (capt), Nel; Toolis, Gilchrist; Skinner, Watson, Bradbury.
In the three other changes made by Eddie Jones, Henry Slade returns at outside centre, with Manu Tuilagi moving to the No 12 jersey, while Mark Wilson and Ben Moon replace Brad Shields and Ellis Genge respectively.
Read more Cokanasigas absence from the entire squad is the biggest surprise, however. Jones bristled at comparisons made last week to the All Blacks great Jonah Lomu by, among others, Sir Clive Woodward, and he is evidently eager to keep a lid on the hype that surrounds the 21-year-old Fiji-born winger. Jones has also hinted that Scotlands pace on the wings played a part his decision. Nowell, meanwhile, did start against Wales but suffered a stinger injury early on in Cardiff and was not risked against Italy.
Apart from Courtney Lawess enforced absence, it is the same XV that lost to Wales in round three, with Joe Launchbury coming into the second row. The Saracens scrum-half, Ben Spencer, is on the bench and appears set to make his first Six Nations appearance while Ben Teo is also among the replacements.
Jones has also resisted any temptation to rekindle the 10-12 axis of George Ford and Owen Farrell, with the former on the bench and the captain again at fly-half. The inclusion of Marcus Smith in the training squad earlier in the week had suggested that Jones was considering starting Ford but Farrell continues in the No 10 jersey. Ben Youngs, meanwhile, makes his 85th appearance, making him Englands most capped scrum-half of all time.
Show Hide England v Scotland: teams England: Elliot Daly; Jack Nowell, Henry Slade, Manu Tuilagi; Jonny May; Owen Farrell (c), Ben Youngs; Ben Moon, Jamie George, Kyle Sinckler, Joe Launchbury, George Kruis, Mark Wilson, Tom Curry, Billy Vunipola.
Replacements: Luke Cowan-Dickie, Ellis Genge, Dan Cole, Brad Shields, Nathan Hughes, Ben Spencer, George Ford, Ben Teo.
Scotland: Sean Maitland; Darcy Graham, Nick Grigg, Sam Johnson,Byron McGuigan; Finn Russell, Ali Price; Allan Dell, Stuart McInally, WP Nel, Ben Toolis, Grant Gilchrist, Sam Skinner, Hamish Watson, Magnus Bradbury.Replacements: Fraser Brown, Gordon Reid, Simon Berghan, Jonny Gray, Josh Strauss, Greig Laidlaw, Adam Hastings, Chris Harris.
Thank you for your feedback. England can claim the Six Nations title for the third time in four years if they beat Scotland and Wales slip up at home to Ireland. Jones said: It is the last week of the tournament so its exciting. It will be a fascinating finish to the championship, with three teams that can win it, and we are playing against one of our most traditional foes in Scotland for the Calcutta Cup. We have had a good preparation and the side is going to be in a great state to play against Scotland on Saturday.
Scotland is a difficult side, they are always at you, they play with a lot of enthusiasm and effort and have got a lot of attacking strings to their bow. Finn Russell is an exceptional player at 10 and they have got some pace on the outside so we are going to have to defend really well against them.