Police were called to Southtown Road at just after 10pm on Tuesday, November 6 to a crash between a black Peugeot 207 and a black Lexmoto Arrow motorcycle.
Police confirmed on Wednesday morning that the rider of the motorcycle, a man in his 20s, had died at the scene.
Any witnesses to the collision or the manner of driving of either vehicle immediately beforehand are requested to contact Norfolk Police. Drivers who were in the area at the time are also requested to review any dash cam footage they may have.
They said a man in his 40s, from the Beccles area, was arrested on suspicion of causing death by dangerous driving and drink driving.
The scene has been cleared this morning with just a few pieces of police tape tied to surrounding areas.
A resident on Southtown Road who did not want to be named was leaving her house to walk her dog when the incident happened.
There was an extremely loud crack and it sounded as though something was being crushed. It was horrifying.
Police can confirm a man has died following a road traffic collision in Great Yarmouth last night (Tuesday 6 November 2018).
The bike came to rest by a gate nearby but I did not see anything more than that. There was lots of police and ambulance services on the scene and it did not quieten down until after two oclock this morning, she said.
Police had tweeted on Tuesday night that the crash, combined with ongoing roadworks, including the closure of the Gapton Hall roundabout, meant the road between Great Yarmouth and Gorleston was closed.
Police have appealed for witnesses to the crash, or anyone who saw the manner of driving of the car or the motorcycle before the crash, to get in touch.
Drivers who were in the area at the time are also being asked to check any dashcam footage and provide that to police.
Anyone who can help should call Andrew Hughes in the serious collision investigation team by email at [email protected] or via 101 quoting incident number 525 of November 6.
Warning drivers about the incident on twitter at around 10.30pm, the force said the road had been cut off by the crash.
Great Yarmouth Police tweeted: Awareness – Serious Road Traffic Collision on Southtown Road, which has cut off road between Great Yarmouth and Gorleston, due to the current road works.