The Extinction Rebellion (XR) group are targeting Marble Arch, Oxford Circus, Waterloo Bridge, and Parliament Square with plans to block the routes for as long as it takes, making it inevitable that they will be arrested for obstruction.
Members of the group, which disrupted the Commons with a nude protest on April 1, will also be gluing or locking themselves to street furniture to delay police by forcing them to use chemicals to free them.
XR, whose prime goal is to reduce carbon emissions to zero by 2025, claims between 3,000 and 6,000 supporters could take part in the protests. Last November, they blocked bridges across London to bring chaos to the capital.
Extinction Rebellion protesters set up camp in Hyde Park ahead of protests across London
Sophie Cowen, an Oxford French graduate who joined the group in November and now acts as media co-ordinator, pledged non-violent civil disobedience: Its 100 per cent about obstructing traffic and making sure we bring it to a standstill. People are willing to be arrested.
The Metropolitan Police said officers would be used from across the service to provide a proportionate response to the protests, which balanced the right to a peaceful protest while ensuring disruption to communities was kept to a minimum.
A spokesman urged travellers to allow extra journey time as road closures and disruptions to the travel network were expected.
Organisers of the Extinction Rebellion group claim up to 30,000 eco-protesters are expected to block major routes from 9am. Scotland Yard warned drivers to expect road closures and widespread disruption in the capital.
It comes as part of attempts to force the Government to declare a climate emergency. Earlier this month, several activists stripped semi-naked in the House of Commons during a Brexit debate.
Video: Climate change protests bring London to a standstill | GME
The movement has received support from actress and activist Dame Emma Thompson and former archbishop of Canterbury Dr Rowan Williams.
Former archbishop of Canterbury Dr Rowan Williams made the chilling warning on the eve mass demonstrations by the Extinction Rebellion group.
Speaking at a meditation on the eve of the protests Dr Williams said humans had declared war on nature.
Ms Perry told The Mail on Sunday she had a good and productive chat with the activists, who have links to Labours far-Left Momentum faction and are preparing a new onslaught of civil disobedience and criminality conceived with military precision to bring Britain to its knees.
He said: "We are here tonight to declare that we do not wish to be at war. We wish to make peace with ourselves by making peace with our neighbour Earth and with our God."
Shut the country down: British climate group Extinction Rebellion heads to US
Thompson has previously said of the demonstrations: "It is time to stand up and save our home."
Organisers said: "The International Rebellion begins and Extinction Rebellion will be bringing London to a standstill for up to two weeks.
News Corp is a network of leading companies in the worlds of diversified media, news, education, and information services.
"They will be blocking five of the citys busiest and most iconic locations in a non-violent, peaceful act of rebellion where they invite people to join them for several days of creative, artist-led resistance."
Demonstrators arrived at Londons Hyde Park on Sunday, some having journeyed to the city on foot in recent weeks from various parts of the UK for what is described as an "International Rebellion".
Environmental protesters will converge at five locations in London today to cause disruption, block roads and shut down the city.
Activists, known as earth marchers, have been making their way in to central London for weeks for the International Rebellion.
And many were encouraged to illegally camp in Hyde Park overnight so they can come together, form relationships, consolidate plans, and gear up for the days ahead, according to campaign group Extinction Rebellion.